CBD for Parkinson’s Disease: 5 Things You Should Know

CBD for Parkinson's Disease
Parkinson’s disease is one of the most common conditions second to Alzheimer’s disease. In the United States, there are about 60,000 new diagnoses in a year of patients suffering from Parkinson’s disease.

Interestingly, several studies show that CBD or cannabinoids found on Cannabis is very potent and can heal various diseases including Parkinson’s disease. In this article, we share the top 5 things you should know about CBD and Parkinson’s disease.

1. CBD and The Endocannabinoid System

One of the many underlying issues causing Parkinson’s disease is the endocannabinoid system or ECS. It is the human body’s natural cannabinoid-releasing machine and internal regulator.

This is a crucial system that helps maintain a healthy and balanced body. However, when it becomes faulty, the problems begin to happen.

In the case of Parkinson’s disease, the ECS, which is to control the cells’ lifespan, is defective. This could have a direct effect on the neurons essential in preventing the beginning of Parkinson’s disease.

CBD has strong antioxidant and neuroprotectant abilities since the cannabinoid works as a team to collect free radicals that cause oxidative stress, the primary cause of PD.

A study conducted by Tel Aviv’s Department of Neurology published in 2014 search for ways on how cannabis could help treat a variety of non-motor and motor symptoms seen among PD patients.

The research studied 22 subjects with PD. These subjects were pre-evaluated on different clinical aspects 30 minutes after smoking pot.

The research discovered that several areas displayed substantial improvement. After smoking cannabis patients showed a massive drop of around 10 percent in terms of the score in the Unified Parkinson Disease Rating Scale.

Additionally, several other motor symptoms showed substantial improvement in terms of sleep and pain scores. The results further suggest that marijuana is particularly potent in treating Parkinson’s disease.

2. Benefits of Using CBD to Treat Parkinson’s Disease

In the health and wellness world, CBD is already gaining popularity. Numerous scientists already confirmed the substance’s potential ability to help treat various health issues like anxiety and pain.

Some of the benefits of using CBD to help treat PD include the following:

Enhanced Sleep Quality

Sleep disorders can also be treated using CBD according to one study. It states that 75 mg to 300 mg of cannabinoid is proven effective in treating and improving sleep disorders. This type is one of the very common side effects among PD patients.

Reduced Psychotic Syndromes

Psychotic syndromes over time develop as Parkinson’s disease progresses in the body. Patients reported having experienced episodes of hallucinating. A small dosage of cannabinoid is proven to minimize the incidence of hallucinations. CBD significantly helps patients handle the disease.


When there is a sustained inflammation in the brain, the dopamine is depleted. When CBD is used, the dopamine level in the brain increased. Several studies show that the reduced level of inflammation slows down the development of the disease.


As a neurodegenerative disease, the cannabinoid is helpful in acting as the neuroprotectant. Additionally, it acts as a potent antioxidant. Many studies reveal that Parkinson’s disease is mainly due to oxidative stress.

3. Ways To Use CBD to Treat Parkinson’s Disease

Cannabinoid can be incorporated in your exercise to minimize the pain. Another alternative way to utilize the CBD during recovery is by taking one after a long day.

Additionally, it can be used as lotion or cream and offers nerve relief to sore body parts. Just a few drops of ingested CBD oil can help control the tremors and shaking more so, slowed movements.

Whether you are an experienced user or a first time user, it is always crucial that you follow the right amount of dosage for the treatment. Begin low and gradually increase based on the symptoms or as prescribed by your doctor.

There are also CBD capsules available that PD patients can use. It is important to note that every person has his or her own unique way of reacting to CBD even if they experience similar symptoms. Therefore, play it smart and start slow, and then observe your body’s reaction to the CBD.

4. Studies About Using CBD For Parkinson’s Disease

There are countless studies conducted over the years that reveal that early detection and diagnosis of Parkinson’s disease could lead to better management. Scientists and researchers continuously develop different kinds of treatment for patients suffering from Parkinson’s disease.

Some of the most recent treatment areas being researched include the use of stem cells, gene therapy, and fetal cell transplantation.

Along with these scientific pieces of evidence are numerous reports of people whose lives were transformed by CBD. While it is not in any way a guarantee that the same will work for all patients, most CBD oil users appear to reap the benefits of the potency of the natural compound called cannabinoid.

Aside from its direct impact on PD patients, CBD also showed several other medical benefits for people suffering from anxiety, insomnia, and depression.

5. Things to Consider Before Buying CBD Oil To be Used for Parkinson’s disease

Dopamine Effect

So far, despite countless pieces of research, it appears that cannabinoid has no direct effect in improving or enhancing the dopamine function. But, it has a neuroprotectant impact on the dopaminergic neurons.

With Parkinson’s disease, treatment using dopaminergic drugs momentarily helps. However, in the long run, it could speed up the dopaminergic neurons’ loss of function. Cannabidiol can slow down the process when it is paired with other neuroprotectants and low doses of dextromethorphan.

It is important to note that dopamine antagonists can help the patient in the short-term. However, in the long-term, it could have the same effect as insulin has to a diabetic. Exposure to the dopamine antagonists could increase the patient’s insensitivity and lead to more fatal health issues.

In Parkinson’s disease, the best way to do is to use any potent substance capable of protecting the brain do its function.

Effective Dosage

If you are in the US or in areas where CBD use is legal for Parkinson’s disease, you can opt to use the prescription Sativex and Epidiolex. Cannabis Therapeutics is a personalized type of medicine and every patient has a unique body response to it.

Generally, the best therapeutic combination could include a synergistic blend of different amounts of THC and CBD. However, patients with Parkinson’s disease with sleep problems or disturbances could benefit from a higher portion of THC during night time.

Different studies about cannabis compiled by Dr. Ethan Russo revealed the following about dosage of cannabis and its potent components. This includes the following:

  • A dose of 300 mg per day of CBD considerably enhanced the quality of life; however, it has no positive impact on the Unified Parkinson Disease Rating Scale.
  • A 0.5 grams of smoked cannabis caused in noteworthy improvement in shakes, bradykinesia, sleep, and tremor.
  • Between 75-300 mg CBD in oral form enriched Sleep disorder’s REM-behavior.

Dr. Russo suggested rational advice for patients with Parkinson’s disease and other chronic illnesses who are considering cannabis therapy. According to him, 2.5 mg of THC is the threshold dosage for the majority of the patients who have no previous tolerance to the effects of THC or cannabis.

He added that 5mg is a clinically acceptable dose with positive effects and one administration. The 10 mg, on the other hand, is a popular dose but could be too high for inexperienced and even to experienced patients.

It is important to note, however, that CBD is not yet an approved medication for patients suffering from Parkinson’s disease. If you are one of those toying with the idea of exploring this territory, it is best that you seek the advice of your physician first.

Start with small doses and observe you body’s response. From there you can slowly increase the amount based on your needs with your doctor’s guidance, of course.

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